Monoclonal antibodies binding renal renin.
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منابع مشابه
Monoclonal antibodies binding renal renin.
Somatic-cell fusion of normal antibody-producing spleen cells with cells from a plasmacytoma culture results in a culture of hybrid cells from which a monoclonal line may be selected. These lines are immortal and may be amplified as tumors in syngeneic animals to produce large quantities of antibodies characterized by molecular homogeneity. We report the application of this technique to the pro...
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Antibodies raised to pure canine renal renin were used to probe homology of renin from other species. Goat, rabbit, and mouse antibodies exhibited similar properties and were specific for renin as confirmed by immunodiffusion, immunoelectrophoresis, and selective inhibition of renin enzymatic activity. Goat antibody also inhibited the enzymatic activities of rat, hog, and bovine renin. Immunolo...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1981
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.3.6_pt_2.ii-4